Fair Value of Financial Instruments - Fair Value of Financial Instruments (Parenthetical) (Detail) $ in Millions	12 Months Ended
	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)
MidCap Credit Facility
Fair Value Of Financial Instruments [Line Items]
Note payable, percentage of hypothetical yield		12
Note payable, percentage of interest rate increases (decreases)	2.00%	2.00%
MidCap Credit Facility | Minimum
Fair Value Of Financial Instruments [Line Items]
Financial liabilities fair value	$ 103.1	$ 35.0
MidCap Credit Facility | Maximum
Fair Value Of Financial Instruments [Line Items]
Financial liabilities fair value		$ 36.0
Mann Group Convertible Note
Fair Value Of Financial Instruments [Line Items]
Note payable, percentage of hypothetical yield		13
Note payable, percentage of interest rate increases (decreases)		2.00%
Mann Group Convertible Note | Volatility
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs		62.7
Mann Group Convertible Note | Minimum
Fair Value Of Financial Instruments [Line Items]
Financial liabilities fair value		$ 14.2
Mann Group Convertible Note | Maximum
Fair Value Of Financial Instruments [Line Items]
Financial liabilities fair value	$ 135.2	$ 14.7
Senior Convertible Notes
Fair Value Of Financial Instruments [Line Items]
Note payable, percentage of hypothetical yield	7.5	11
Note payable, percentage of interest rate increases (decreases)	2.00%	2.00%
Senior Convertible Notes | Volatility
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs	49.5	62.7
Senior Convertible Notes | Minimum
Fair Value Of Financial Instruments [Line Items]
Financial liabilities fair value	$ 46.2	$ 224.1
Senior Convertible Notes | Maximum
Fair Value Of Financial Instruments [Line Items]
Financial liabilities fair value	$ 47.6	$ 238.9
Milestone Rights | Risk-Free Rate
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs	4.5	3.88
Milestone Rights | Dividend Yield
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs	0	0
Milestone Rights | Volatility
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs	45	50
Milestone Rights | Period
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs	7	8
Milestone Rights | Credit Risk
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs	11	17
Contingent Milestone Liability | Risk-Free Rate
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs		4.01
Contingent Milestone Liability | Dividend Yield
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs		0
Contingent Milestone Liability | Volatility
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs		43
Contingent Milestone Liability | Period
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs		15
Contingent Milestone Liability | Credit Risk
Fair Value Of Financial Instruments [Line Items]
Note payable, fair value key inputs		17
Financing Liability
Fair Value Of Financial Instruments [Line Items]
Note payable, percentage of hypothetical yield	8	9.5
Liability for Sale of Future Royalties
Fair Value Of Financial Instruments [Line Items]
Note payable, percentage of hypothetical yield	9
Note payable, percentage of interest rate increases (decreases)	2.00%
Liability for Sale of Future Royalties | Minimum
Fair Value Of Financial Instruments [Line Items]
Financial liabilities fair value	$ 137.9
Liability for Sale of Future Royalties | Maximum
Fair Value Of Financial Instruments [Line Items]
Financial liabilities fair value	$ 180.0