Collaborations, Licensing and Other Arrangements - Summary of UT Revenue (Parenthetical) (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenue from UT	$ 285,504	$ 198,962	$ 99,770
United Therapeutics Corporation [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenue from UT	201,428	124,786	42,851
United Therapeutics Corporation [Member] | Contract Asset
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenue from UT	$ 24,300	$ 21,700	$ 9,100