Collaboration, Licensing and Other Arrangements - Summary of UT Revenue (Detail) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2024	Mar. 31, 2023
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue from UT	$ 66,263	$ 40,626
United Therapeutics Corporation
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue from UT	47,462	23,027
United Therapeutics Corporation | Commercial Supply
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue from UT	24,464	11,164
United Therapeutics Corporation | License Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue from UT	347	185
United Therapeutics Corporation | Royalties Arrangement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue from UT	$ 22,651	$ 11,678