Condensed Consolidated Statements of Cash Flows (Unaudited) (USD $) In Thousands	6 Months Ended		248 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss	$ (86,005)	$ (86,951)	$ (1,860,747)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	8,023	8,607	104,486
Stock-based compensation expense	4,701	8,005	118,123
Stock expense for shares issued pursuant to research agreement			3,018
(Gain) loss on sale, abandonment/disposal or impairment of property and equipment	(63)		23,512
Accrued interest on investments, net of amortization of discounts			(191)
In-process research and development			19,726
Goodwill impairment			151,428
Loss on available-for-sale securities		347	873
Other, net	9	(6)	1,113
Changes in assets and liabilities:
State research and development credit exchange receivable	418	1,066	(885)
Prepaid expenses and other current assets	1,256	1,221	7
Other assets	87		(230)
Accounts payable	(447)	(3,810)	1,255
Accrued expenses and other current liabilities	4,574	(3,313)	18,503
Other liabilities			(2)
Net cash used in operating activities	(67,447)	(74,834)	(1,420,011)
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchase of marketable securities			(796,779)
Sales and maturities of marketable securities	3,828		796,393
Purchase of property and equipment	(6,109)	(4,052)	(326,360)
Proceeds from sale of property and equipment	63		347
Net cash used in investing activities	(2,218)	(4,052)	(326,399)
CASH FLOWS FROM FINANCING ACTIVITIES:
Issuance of common stock and warrants	10,424	1,527	1,229,504
Collection of Series C convertible preferred stock subscriptions receivable			50,000
Issuance of Series B convertible preferred stock for cash			15,000
Cash received for common stock to be issued			3,900
Repurchase of common stock			(1,028)
Put shares sold to majority stockholder			623
Borrowings under lines of credit			4,220
Proceeds from notes receivables			1,742
Borrowings on notes payable to related party	18,000	77,000	340,000
Principal payments on notes payable to principal stockholder			(70,000)
Borrowings on notes payable			3,460
Principal payments on notes payable			(1,667)
Proceeds from senior convertible notes			207,050
Payment of employment taxes related to vested restricted stock units	(50)	(1,302)	(11,624)
Net cash provided by financing activities	28,374	77,225	1,771,180
NET (DECREASE) INCREASE IN CASH AND CASH EQUIVALENTS	(41,291)	(1,661)	24,770
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD	66,061	30,019
CASH AND CASH EQUIVALENTS, END OF PERIOD	24,770	28,358	24,770
SUPPLEMENTAL CASH FLOWS DISCLOSURES:
Cash paid for income taxes			26
Interest paid in cash	10,136	6,131	42,285
Accretion on redeemable preferred stock			(952)
Issuance of common stock upon conversion of notes payable			3,331
Increase in additional paid-in capital resulting from merger			171,154
Issuance of common stock for notes receivable			2,758
Issuance of put option by stockholder			(2,949)
Put option redemption by stockholder			1,921
Issuance of Series C convertible preferred stock subscriptions			50,000
Issuance of Series A redeemable convertible preferred stock			4,296
Conversion of Series A redeemable convertible preferred stock			(5,248)
Non-cash construction in progress and property and equipment	1,039	459	1,039
Cancellation of principal on note payable to related party	$ 11,116		$ 27,797