Condensed Consolidated Statements of Operations (Unaudited) (USD $) In Thousands, except Per Share data	3 Months Ended		6 Months Ended		248 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011
Condensed Consolidated Statements of Operations [Abstract]
Revenue		$ 93	$ 50	$ 93	$ 3,131
Operating expenses:
Research and development	30,296	26,160	56,585	56,651	1,322,677
General and administrative	8,890	11,196	20,652	21,306	360,253
In-process research and development costs					19,726
Goodwill impairment					151,428
Total operating expenses	39,186	37,356	77,237	77,957	1,854,084
Loss from operations	(39,186)	(37,263)	(77,187)	(77,864)	(1,850,953)
Other income (expense)	47	(1,257)	1,397	(2,047)	(1,220)
Interest expense on note payable to related party	(2,509)	(2,523)	(4,985)	(4,625)	(22,436)
Interest expense on senior convertible notes	(2,834)	(1,211)	(5,247)	(2,421)	(23,100)
Interest income	2	3	17	6	36,988
Loss before provision for income taxes	(44,480)	(42,251)	(86,005)	(86,951)	(1,860,721)
Income taxes					(26)
Net loss	(44,480)	(42,251)	(86,005)	(86,951)	(1,860,747)
Deemed dividend related to beneficial conversion feature of convertible preferred stock					(22,260)
Accretion on redeemable preferred stock					(952)
Net loss applicable to common stockholders	$ (44,480)	$ (42,251)	$ (86,005)	$ (86,951)	$ (1,883,959)
Net loss per share applicable to common stockholders - basic and diluted	$ (0.37)	$ (0.37)	$ (0.71)	$ (0.77)
Shares used to compute basic and diluted net loss per share applicable to common stockholders	121,708	113,116	121,385	113,105	0