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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001144204-07-005502.txt : 20070206
<SEC-HEADER>0001144204-07-005502.hdr.sgml : 20070206
<ACCEPTANCE-DATETIME>20070206161510
ACCESSION NUMBER:		0001144204-07-005502
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20070201
FILED AS OF DATE:		20070206
DATE AS OF CHANGE:		20070206

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CALYPTE BIOMEDICAL CORP
		CENTRAL INDEX KEY:			0000899426
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				061226727
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		5000 HOPYARD ROAD, SUITE 480
		CITY:			PLEASANTON
		STATE:			CA
		ZIP:			94588
		BUSINESS PHONE:		9257307200

	MAIL ADDRESS:	
		STREET 1:		5000 HOPYARD ROAD, SUITE 480
		CITY:			PLEASANTON
		STATE:			CA
		ZIP:			94588

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			DOTSON JERROLD DUANE
		CENTRAL INDEX KEY:			0001388853

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32280
		FILM NUMBER:		07584672

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		971 204 0282

	MAIL ADDRESS:	
		STREET 1:		5 CENTERPOINTE DRIVE
		STREET 2:		SUITE 400
		CITY:			LAKE OSWEGO
		STATE:			OR
		ZIP:			97035
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>v064635_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2007-02-01</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000899426</issuerCik>
        <issuerName>CALYPTE BIOMEDICAL CORP</issuerName>
        <issuerTradingSymbol>CBMC</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001388853</rptOwnerCik>
            <rptOwnerName>DOTSON JERROLD DUANE</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5 CENTERPOINTE DRIVE</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 400</rptOwnerStreet2>
            <rptOwnerCity>LAKE OSWEGO</rptOwnerCity>
            <rptOwnerState>OR</rptOwnerState>
            <rptOwnerZipCode>97035</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>VP Fin &amp; Admin, Corp Secretary</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>20744</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Stock option</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>.32</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2003-05-29</value>
            </exerciseDate>
            <expirationDate>
                <value>2013-05-29</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>31266</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Stock option</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>.32</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2003-11-29</value>
            </exerciseDate>
            <expirationDate>
                <value>2013-05-29</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>80000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Stock option</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>.585</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2004-06-22</value>
            </exerciseDate>
            <expirationDate>
                <value>2014-06-22</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>2000000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Represents option to purchase common stock.  Options to purchase all shares reported are currently exercisable</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Jerrold D. Dotson</signatureName>
        <signatureDate>2007-02-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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