<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/nport" xmlns:com="http://www.sec.gov/edgar/common" xmlns:ncom="http://www.sec.gov/edgar/nportcommon" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.sec.gov/edgar/nport eis_NPORT_Filer.xsd">
  <headerData>
    <submissionType>NPORT-P</submissionType>
    <isConfidential>false</isConfidential>
    <filerInfo>

      <filer>
        <issuerCredentials>
          <cik>0000899148</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>


      <seriesClassInfo>
        <seriesId>S000018293</seriesId>
        <classId>C000050428</classId>
        <classId>C000050430</classId>
        <classId>C000050429</classId>
      </seriesClassInfo>

    </filerInfo>
  </headerData>
  <formData>
    <genInfo>
      <regName>Rydex Series Funds</regName>
      <regFileNumber>811-07584</regFileNumber>
      <regCik>0000899148</regCik>
      <regLei>5493004D62WV1EDNTU07</regLei>
      <regStreet1>702 King Farm Blvd., Suite 200</regStreet1>
      <regCity>Rockville</regCity>
      <regStateConditional regCountry="US" regState="US-MD"/>
      <regZipOrPostalCode>20850</regZipOrPostalCode>
      <regPhone>301-296-5100</regPhone>
      <seriesName>Japan 2x Strategy Fund</seriesName>
      <seriesId>S000018293</seriesId>
      <seriesLei>549300TYQ6P1QBF6GR37</seriesLei>
      <repPdEnd>2021-03-31</repPdEnd>
      <repPdDate>2020-09-30</repPdDate>
      <isFinalFiling>N</isFinalFiling>
    </genInfo>
    <fundInfo>
      <totAssets>1610319.53</totAssets>
      <totLiabs>3253.42</totLiabs>
      <netAssets>1607066.11</netAssets>
      <assetsAttrMiscSec>0.00000000</assetsAttrMiscSec>
      <assetsInvested>0.00000000</assetsInvested>
      <amtPayOneYrBanksBorr>0.00000000</amtPayOneYrBanksBorr>
      <amtPayOneYrCtrldComp>0.00000000</amtPayOneYrCtrldComp>
      <amtPayOneYrOthAffil>0.00000000</amtPayOneYrOthAffil>
      <amtPayOneYrOther>0.00000000</amtPayOneYrOther>
      <amtPayAftOneYrBanksBorr>0.00000000</amtPayAftOneYrBanksBorr>
      <amtPayAftOneYrCtrldComp>0.00000000</amtPayAftOneYrCtrldComp>
      <amtPayAftOneYrOthAffil>0.00000000</amtPayAftOneYrOthAffil>
      <amtPayAftOneYrOther>0.00000000</amtPayAftOneYrOther>
      <delayDeliv>0.00000000</delayDeliv>
      <standByCommit>0.00000000</standByCommit>
      <liquidPref>0.00000000</liquidPref>
      <cshNotRptdInCorD>0.00000000</cshNotRptdInCorD>
      <curMetrics>
        <curMetric>
          <curCd>USD</curCd>
          <intrstRtRiskdv01 period10Yr="6.47298084" period1Yr="3.97127116" period30Yr="1.81536568" period3Mon="4.82532005" period5Yr="14.76692899"/>
          <intrstRtRiskdv100 period10Yr="647.29808358" period1Yr="397.12711610" period30Yr="119.70793251" period3Mon="482.53200549" period5Yr="782.16278793"/>
        </curMetric>
      </curMetrics>
      <creditSprdRiskInvstGrade period10Yr="0.00000000" period1Yr="80.19470434" period30Yr="0.00000000" period3Mon="0.00000000" period5Yr="19.15632018"/>
      <creditSprdRiskNonInvstGrade period10Yr="0.00000000" period1Yr="0.00000000" period30Yr="0.00000000" period3Mon="0.00000000" period5Yr="0.00000000"/>
      <isNonCashCollateral>N</isNonCashCollateral>
      <returnInfo>
        <monthlyTotReturns>
          <monthlyTotReturn classId="C000050429" rtn1="-0.31410300" rtn2="10.90828400" rtn3="3.02130000"/>
          <monthlyTotReturn classId="C000050428" rtn1="-0.24682800" rtn2="10.98107700" rtn3="3.07506900"/>
          <monthlyTotReturn classId="C000050430" rtn1="-0.23793900" rtn2="10.97754800" rtn3="3.07973800"/>
        </monthlyTotReturns>
        <monthlyReturnCats>
          <equityContracts>
            <mon1 netRealizedGain="-36267.87000000" netUnrealizedAppr="-40569.14000000"/>
            <mon2 netRealizedGain="-35819.00000000" netUnrealizedAppr="176139.20000000"/>
            <mon3 netRealizedGain="18594.85000000" netUnrealizedAppr="2258.64000000"/>
            <futureCategory>
              <instrMon1 netRealizedGain="-36267.87000000" netUnrealizedAppr="-40569.14000000"/>
              <instrMon2 netRealizedGain="-35819.00000000" netUnrealizedAppr="176139.20000000"/>
              <instrMon3 netRealizedGain="18594.85000000" netUnrealizedAppr="2258.64000000"/>
            </futureCategory>
          </equityContracts>
          <foreignExchgContracts>
            <mon1 netRealizedGain="12203.38000000" netUnrealizedAppr="45577.30000000"/>
            <mon2 netRealizedGain="1062.65000000" netUnrealizedAppr="1817.60000000"/>
            <mon3 netRealizedGain="36950.52000000" netUnrealizedAppr="-25796.42000000"/>
            <futureCategory>
              <instrMon1 netRealizedGain="12203.38000000" netUnrealizedAppr="45577.30000000"/>
              <instrMon2 netRealizedGain="1062.65000000" netUnrealizedAppr="1817.60000000"/>
              <instrMon3 netRealizedGain="36950.52000000" netUnrealizedAppr="-25796.42000000"/>
            </futureCategory>
          </foreignExchgContracts>
        </monthlyReturnCats>
        <othMon1 netRealizedGain="0.00000000" netUnrealizedAppr="863.82000000"/>
        <othMon2 netRealizedGain="0.00000000" netUnrealizedAppr="1022.93000000"/>
        <othMon3 netRealizedGain="0.00000000" netUnrealizedAppr="350.81000000"/>
      </returnInfo>
      <mon1Flow redemption="645761.03000000" reinvestment="0.00000000" sales="872767.57000000"/>
      <mon2Flow redemption="681755.53000000" reinvestment="0.00000000" sales="463855.66000000"/>
      <mon3Flow redemption="1181675.08000000" reinvestment="0.00000000" sales="1406993.52000000"/>


    </fundInfo>
    <invstOrSecs>
      <invstOrSec>
        <name>Chicago Mercantile Exchange</name>
        <lei>N/A</lei>
        <title>Japanese Yen Futures Contracts</title>
        <cusip>N/A</cusip>
        <identifiers>
          <ticker value="JYZ0"/>
        </identifiers>
        <balance>27.00000000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>17939.80000000</valUSD>
        <pctVal>1.116307530123</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DFE</assetCat>
        <issuerConditional desc="Derivative" issuerCat="OTHER"/>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <derivativeInfo>
          <futrDeriv derivCat="FUT">
            <counterparties>
              <counterpartyName>Goldman Sachs &amp; Co. LLC</counterpartyName>
              <counterpartyLei>FOR8UP27PHTHYVLBNG30</counterpartyLei>
            </counterparties>
            <payOffProf>Long</payOffProf>
            <descRefInstrmnt>
              <otherRefInst>
                <issuerName>N/A</issuerName>
                <issueTitle>Japanese Yen</issueTitle>
                <identifiers>
                  <cusip value="N/A"/>
                  <other otherDesc="Currency" value="Japanese Yen"/>
                </identifiers>
              </otherRefInst>
            </descRefInstrmnt>
            <expDate>2020-12-14</expDate>
            <notionalAmt>3184260.20000000</notionalAmt>
            <curCd>USD</curCd>
            <unrealizedAppr>17939.80000000</unrealizedAppr>
          </futrDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Guggenheim Partners Investment Management LLC</name>
        <lei>N/A</lei>
        <title>Guggenheim Ultra Short Duration Fund - Institutional Class</title>
        <cusip>40169J523</cusip>
        <identifiers>
          <isin value="US40169J5231"/>
        </identifiers>
        <balance>14445.93100000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>144170.39000000</valUSD>
        <pctVal>8.971030445038</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FEDERAL FARM CREDIT BANK</name>
        <lei>N/A</lei>
        <title>Federal Farm Credit Bank</title>
        <cusip>3133EKCY0</cusip>
        <identifiers>
          <isin value="US3133EKCY02"/>
        </identifiers>
        <balance>100000.00000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>100405.03000000</valUSD>
        <pctVal>6.247722441237</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>USGSE</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <debtSec>
          <maturityDt>2022-03-14</maturityDt>
          <couponKind>Floating</couponKind>
          <annualizedRt>0.45000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Chicago Mercantile Exchange</name>
        <lei>N/A</lei>
        <title>Nikkei 225 (CME) Index Futures Contracts</title>
        <cusip>N/A</cusip>
        <identifiers>
          <ticker value="NXZ0"/>
        </identifiers>
        <balance>28.00000000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>47300.60000000</valUSD>
        <pctVal>2.943288997613</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="Derivative" issuerCat="OTHER"/>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <derivativeInfo>
          <futrDeriv derivCat="FUT">
            <counterparties>
              <counterpartyName>Goldman Sachs &amp; Co. LLC</counterpartyName>
              <counterpartyLei>FOR8UP27PHTHYVLBNG30</counterpartyLei>
            </counterparties>
            <payOffProf>Long</payOffProf>
            <descRefInstrmnt>
              <indexBasketInfo>
                <indexName>Nikkei 225</indexName>
                <indexIdentifier>JP9010C00002</indexIdentifier>
              </indexBasketInfo>
            </descRefInstrmnt>
            <expDate>2020-12-10</expDate>
            <notionalAmt>3217499.40000000</notionalAmt>
            <curCd>USD</curCd>
            <unrealizedAppr>47300.60000000</unrealizedAppr>
          </futrDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FEDERAL FARM CREDIT BANK</name>
        <lei>N/A</lei>
        <title>Federal Farm Credit Bank</title>
        <cusip>3133EKGP5</cusip>
        <identifiers>
          <isin value="US3133EKGP58"/>
        </identifiers>
        <balance>100000.00000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>100326.54000000</valUSD>
        <pctVal>6.242838385783</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>USGSE</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <debtSec>
          <maturityDt>2022-04-11</maturityDt>
          <couponKind>Floating</couponKind>
          <annualizedRt>0.39000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BOFA SECURITIES, INC.</name>
        <lei>549300HN4UKV1E2R3U73</lei>
        <title>BofA Securities, Inc.</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="REPO-BANK"/>
        </identifiers>
        <balance>221095.77000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>221095.77000000</valUSD>
        <pctVal>13.75772711677</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>RA</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <repurchaseAgrmt>
          <transCat>Repurchase</transCat>
          <notClearedCentCparty isCleared="N">
            <counterpartyInfos>
              <counterpartyInfo lei="549300HN4UKV1E2R3U73" name="BOFA SECURITIES, INC."/>
            </counterpartyInfos>
          </notClearedCentCparty>
          <isTriParty>Y</isTriParty>
          <repurchaseRt>0.06000000</repurchaseRt>
          <maturityDt>2020-10-01</maturityDt>
          <repurchaseCollaterals>
            <repurchaseCollateral>
              <principalAmt>199595.61000000</principalAmt>
              <principalCd>USD</principalCd>
              <collateralVal>225518.08000000</collateralVal>
              <collateralCd>USD</collateralCd>
              <invstCat>UST</invstCat>
            </repurchaseCollateral>
          </repurchaseCollaterals>
        </repurchaseAgrmt>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>J.P. MORGAN SECURITIES LLC</name>
        <lei>ZBUT11V806EZRVTWT807</lei>
        <title>J.P. Morgan Securities LLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="REPO-JP M"/>
        </identifiers>
        <balance>531189.31000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>531189.31000000</valUSD>
        <pctVal>33.05335771158</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>RA</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <repurchaseAgrmt>
          <transCat>Repurchase</transCat>
          <notClearedCentCparty isCleared="N">
            <counterpartyInfos>
              <counterpartyInfo lei="ZBUT11V806EZRVTWT807" name="J.P. MORGAN SECURITIES LLC"/>
            </counterpartyInfos>
          </notClearedCentCparty>
          <isTriParty>Y</isTriParty>
          <repurchaseRt>0.06000000</repurchaseRt>
          <maturityDt>2020-10-01</maturityDt>
          <repurchaseCollaterals>
            <repurchaseCollateral>
              <principalAmt>496360.39000000</principalAmt>
              <principalCd>USD</principalCd>
              <collateralVal>541813.41000000</collateralVal>
              <collateralCd>USD</collateralCd>
              <invstCat>UST</invstCat>
            </repurchaseCollateral>
          </repurchaseCollaterals>
        </repurchaseAgrmt>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BARCLAYS CAPITAL INC.</name>
        <lei>AC28XWWI3WIBK2824319</lei>
        <title>Barclays Capital, Inc.</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="REPO-BARC"/>
        </identifiers>
        <balance>201197.15000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>201197.15000000</valUSD>
        <pctVal>12.51953163270</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>RA</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <repurchaseAgrmt>
          <transCat>Repurchase</transCat>
          <notClearedCentCparty isCleared="N">
            <counterpartyInfos>
              <counterpartyInfo lei="AC28XWWI3WIBK2824319" name="BARCLAYS CAPITAL INC."/>
            </counterpartyInfos>
          </notClearedCentCparty>
          <isTriParty>Y</isTriParty>
          <repurchaseRt>0.06000000</repurchaseRt>
          <maturityDt>2020-10-01</maturityDt>
          <repurchaseCollaterals>
            <repurchaseCollateral>
              <principalAmt>209213.21000000</principalAmt>
              <principalCd>USD</principalCd>
              <collateralVal>205221.27000000</collateralVal>
              <collateralCd>USD</collateralCd>
              <invstCat>UST</invstCat>
            </repurchaseCollateral>
          </repurchaseCollaterals>
        </repurchaseAgrmt>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Guggenheim Partners Investment Management LLC</name>
        <lei>N/A</lei>
        <title>Guggenheim Strategy Fund II</title>
        <cusip>N/A</cusip>
        <identifiers>
          <ticker value="GFSBX"/>
        </identifiers>
        <balance>4036.42800000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>100789.61000000</valUSD>
        <pctVal>6.271653006235</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TREASURY BILL</name>
        <lei>254900HROIFWPRGM1V77</lei>
        <title>U.S. Treasury Bills</title>
        <cusip>9127962R9</cusip>
        <identifiers>
          <isin value="US9127962R96"/>
        </identifiers>
        <balance>218000.00000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>217993.43000000</valUSD>
        <pctVal>13.56468340932</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>UST</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <debtSec>
          <maturityDt>2020-10-15</maturityDt>
          <couponKind>None</couponKind>
          <annualizedRt>0.00000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <signature>
      <ncom:dateSigned>2020-10-30</ncom:dateSigned>
      <ncom:nameOfApplicant>Rydex Series Funds</ncom:nameOfApplicant>
      <ncom:signature>John Sullivan</ncom:signature>
      <ncom:signerName>John Sullivan</ncom:signerName>
      <ncom:title>CFO</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
