Note 10 - Accrued Expenses and Other Liabilities - Summary of Accrued Expenses (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Compensation and related expenses	$ 9,523	$ 7,345
Professional fees	3,590	3,438
Clinical trial costs	1,961	1,429
Other	1,059	996
Total	17,847	14,793
Accrued Expenses and Other Current Liabilities [Member]
Operating lease liability - current	1,526	1,437
Finance lease liability - current	$ 188	$ 148