Note 15 - Product Revenue by Product Group (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Orthobiologics [Member]
Product revenue	$ 22,428	$ 20,461	$ 65,319	$ 51,717
Surgical [Member]
Product revenue	1,173	1,413	3,924	4,450
Dermal [Member]
Product revenue	594	412	1,558	1,132
Other [Member]
Product revenue	1,588	1,390	3,835	4,790
Product revenue	$ 25,783	$ 23,676	$ 74,636	$ 62,089