X0306 4 2016-02-24 0 0000898437 Anika Therapeutics, Inc. ANIK 0001623597 Ahn Edward S. 32 WIGGINS AVENUE BEDFORD MA 01730 0 1 0 0 Chief Tech & Strategy Officer Stock Option (Right to Buy) 39.69 2016-02-24 4 A 0 3325 0 A 2025-02-03 Common Stock 3325 3325 D The exercise price of the stock options represents the closing price of the Company's common stock on the grant date, February 3, 2015, the date the Compensation Committee of the Company granted these performance-based stock option awards (the "Performance Grant"). Please also see notes 2 and 3. On February 24, 2016, the Compensation Committee determined and certified that 87.5% of the initial Performance Grant had been earned, subject to time-based vesting. Please also see notes 1 and 3. The stock options vest in four equal installments on the following dates: February 24, 2016, January 1, 2017, January 1, 2018 and January 1, 2019. /s/ Edward S. Ahn 2016-02-26