X0306 4 2019-12-23 0 0001645460 Cue Biopharma, Inc. CUE 0000897744 MARLETT CHRISTOPHER A 2425 CEDAR SPRINGS ROAD DALLAS TX 75201 1 0 0 0 Common Stock 2019-12-23 4 S 0 17000 16.82 D 803850 I See footnote Common Stock 2019-12-26 4 S 0 19647 17.53 D 784203 I See footnote Common Stock 9000 D The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.44 to $17.00, inclusive. The reporting person undertakes to provide to Cue Biopharma, Inc. (the "Issuer"), any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. Held by the Christopher A. Marlett Living Trust, of which the reporting person is sole trustee. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $17.35 to $17.84, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. /s/ Christopher Marlett by Mark R. Busch, attorney-in-fact 2019-12-27