Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2020

Accounting Policies [Abstract]

Summary of Impact of Accounts Receivable Reserves on Gross Trade Accounts Receivable Balances

The following table summarizes the impact of accounts receivable reserves on the gross trade accounts receivable balances at December 31, 2020 and 2019:

In thousands	December 31, 2020			December 31, 2019
Gross trade accounts receivable	$	203,875		$	149,567
Trade allowances		(36,242	)		(29,261	)
Chargebacks	$	(12,114	)		(3,876	)
Allowance for doubtful accounts		(945	)		—
Accounts receivable, net	$	154,574		$	116,430

Calculation of Net Loss and Number of Shares Used to Compute Basic and Diluted Net Loss per Share

The calculation of net loss and the number of shares used to compute basic and diluted net loss per share for the years ended December 31, 2020, 2019, and 2018 are as follows:

In thousands	2020			2019			2018
Net loss—basic and diluted	$	(18,000	)	$	(22,645	)	$	(116,445	)
Weighted average shares outstanding—basic and diluted		381,759			342,538			297,237
Net loss per share—basic and diluted	$	(0.05	)	$	(0.07	)	$	(0.39	)

Anti-Dilutive Securities Not Included in the Computation of Net Loss or Earnings per Share

For the years ended December 31, 2020, 2019 and 2018, the following potentially dilutive securities were not included in the computation of net loss per share because the effect would be anti-dilutive:

In thousands	2020		2019		2018
Stock options		16,664		15,619		19,263
Restricted stock and restricted stock units		7,710		6,921		9,633
Preferred stock (if converted)		—		28,932		28,932

Estimated Fair Value of Assets and Liability

The following tables present information about the estimated fair value of the Company’s assets and liabilities as of December 31, 2020 and 2019 and indicate the fair value hierarchy of the valuation techniques the Company utilized to determine such fair value:

	December 31, 2020
In thousands	Total		Level 1		Level 2		Level 3
Asset:
Money Market Fund	$	88,266	$	88,266	$	—	$	—
U.S. Treasury Shares		48,356		48,356		—		—
Corporate Bonds		179,864		—		179,864		—
Commercial Paper		106,650		—		106,650		—
Agency Securities		20,782		—		20,782		—
Repo Securities		10,000		—		10,000		—
Asset Backed Securities		8,599		—		8,599		—
Certificate of Deposit		6,125		—		6,125		—
Non-US Government		5,240		—		5,240		—
Total	$	473,882	$	136,622	$	337,260	$	—

	December 31, 2019
In thousands	Total		Level 1		Level 2		Level 3
Asset:
Money Market Fund	$	10,078	$	10,078	$	—	$	—

Carrying Amounts and Estimated Fair Values of Debt from Royalty-Bearing Instrument

The carrying amounts of accounts payable and accrued liabilities approximate fair value because of their short-term nature. The carrying amounts and the estimated fair values of the debt from royalty-bearing instrument as of December 31, 2020 and 2019 are as follows:

	December 31, 2020				December 31, 2019
In thousands	Carrying Value		Estimated Fair Value		Carrying Value		Estimated Fair Value
Debt from royalty-bearing instrument	$	—	$	—	$	49,702	$	50,400