Accounts receivable credit period

No definition available.

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- Definition

Cash discount percent.

+ References

No definition available.

+ Details

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- Definition

Debt instrument aggregate principal amount redeemed.

+ References

No definition available.

+ Details

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- Definition

Fair value assumptions, comparable yield to maturity.

+ References

No definition available.

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- Definition

Fair value assumptions coupon rate.

+ References

No definition available.

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- Definition

Significant accounting policies.

+ References

No definition available.

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- Definition

Write offs of accounts receivables.

+ References

No definition available.

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- Definition

For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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- Definition

The portion of the carrying value of long-term convertible debt as of the balance sheet date that is scheduled to be repaid within one year or in the normal operating cycle if longer. Convertible debt is a financial instrument which can be exchanged for a specified amount of another security, typically the entity's common stock, at the option of the issuer or the holder.

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- Definition

Face (par) amount of the original debt instrument that was repurchased.

+ References

No definition available.

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- Definition

Period of time between issuance and maturity of debt instrument, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

No definition available.

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- Definition

Amount, after accumulated amortization, of debt discount.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
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-Name Accounting Standards Codification
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-SubTopic 30
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- Definition

Fair value as of the balance sheet date of the embedded derivative or group of embedded derivatives classified as a liability.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 815
-SubTopic 10
-Section 50
-Paragraph 4B
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- Definition

Period the instrument, asset or liability is expected to be outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

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- Definition

Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues.

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No definition available.

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- Definition

Minimum amount of other commitment not otherwise specified in the taxonomy. Excludes commitments explicitly modeled in the taxonomy, including but not limited to, long-term and short-term purchase commitments, recorded and unrecorded purchase obligations, supply commitments, registration payment arrangements, leases, debt, product warranties, guarantees, environmental remediation obligations, and pensions.

+ References

No definition available.

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- Definition

The cash outflow during the period from the repayment of aggregate short-term and long-term debt. Excludes payment of capital lease obligations.

+ References

No definition available.

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- Definition

Including the current and noncurrent portions, carrying value as of the balance sheet date of Notes with the highest claim on the assets of the issuer in case of bankruptcy or liquidation (with maturities initially due after one year or beyond the operating cycle if longer). Senior note holders are paid off in full before any payments are made to junior note holders.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
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-Name Accounting Standards Codification
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- Definition

The net change in the difference between the fair value and the carrying value, or in the comparative fair values, of derivative instruments, including options, swaps, futures, and forward contracts, held at each balance sheet date, that was included in earnings for the period.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
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-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 28
-Subparagraph (b)
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Significant Accounting Policies - Additional Information (Detail)	1 Months Ended		3 Months Ended		6 Months Ended		12 Months Ended
	Jan. 31, 2017 USD ($)	Jan. 31, 2012	Mar. 31, 2017 USD ($)	Jun. 30, 2016 USD ($)	Jun. 30, 2017 USD ($) Segment	Jun. 30, 2016 USD ($)	Dec. 31, 2016 USD ($)	Jan. 20, 2017 USD ($)	Dec. 31, 2015 USD ($)	Nov. 30, 2015 USD ($)	May 31, 2014 USD ($)	Dec. 31, 2012 USD ($)
Significant Accounting Policies [Line Items]
Sales discount percentage					2.00%
Trade receivables, credit period					30 days
Accounts receivable written off					$ 0
Gain (loss) on change in fair value of derivative liabilities				$ 5,810,000		$ 4,560,000
Number of operating segments \| Segment					1
Embedded Derivative Financial Instruments \| BioPharma Debt
Significant Accounting Policies [Line Items]
Maximum repayment of future revenue and receivables												$ 150,000,000
Fair value of embedded derivative liability				2,800,000	$ 0	2,800,000	$ 0		$ 5,500,000
Gain (loss) on change in fair value of derivative liabilities					$ 0	$ 2,700,000
Embedded Derivative Financial Instruments \| BioPharma Debt \| Minimum
Significant Accounting Policies [Line Items]
Derivative liability fair value assumptions, term					1 year 10 months 25 days		2 years 4 months 24 days
Derivative liability fair value assumption, coupon rate					8.10%		8.10%
Derivative liability fair value assumptions, market yields					8.10%		11.90%
Embedded Derivative Financial Instruments \| BioPharma Debt \| Maximum
Significant Accounting Policies [Line Items]
Derivative liability fair value assumptions, term					4 years 6 months		5 years
Derivative liability fair value assumption, coupon rate					11.10%		11.10%
Derivative liability fair value assumptions, market yields					17.50%		18.40%
Top Three Customers \| Gross Product Sales \| Customer Concentration Risk
Significant Accounting Policies [Line Items]
Concentration risk percentage					92.00%	95.00%
Top Three Customers \| Accounts Receivable \| Customer Concentration Risk
Significant Accounting Policies [Line Items]
Concentration risk percentage					86.00%	94.00%
2012 Notes
Significant Accounting Policies [Line Items]
Aggregate principal amount of notes	$ 15,000,000
Aggregate principal amount redeemed	100,000
2017 Notes
Significant Accounting Policies [Line Items]
Aggregate principal amount of notes					$ 30,000,000
Convertible senior notes, discount					$ 1,200,000
Convertible Debt \| 2012 Notes
Significant Accounting Policies [Line Items]
Aggregate principal amount of notes							$ 15,107,000
Convertible senior notes, discount							$ 0
Note, expected term		24 months			24 months
Convertible senior notes, principal amount purchase	$ 15,000,000		$ 15,000,000							$ 16,200,000
Convertible senior notes, aggregate principal amount redeemed			$ 100,000		$ 100,000
Convertible senior notes, outstanding amount					0
Convertible Debt \| 2017 Notes
Significant Accounting Policies [Line Items]
Convertible senior notes, discount					1,100,000			$ 1,200,000
Convertible Debt \| 2014 Notes
Significant Accounting Policies [Line Items]
Convertible senior notes, discount											$ 27,900,000
Fair value of embedded derivative liability				600,000		$ 600,000			2,100,000
Gain (loss) on change in fair value of derivative liabilities						1,500,000
Convertible Debt \| 2014 Notes and 2015 Notes
Significant Accounting Policies [Line Items]
Gain (loss) on change in fair value of derivative liabilities					$ 0
Convertible Debt \| 2015 Notes
Significant Accounting Policies [Line Items]
Convertible senior notes, discount										$ 3,800,000
Fair value of embedded derivative liability				$ 200,000		200,000			$ 600,000
Gain (loss) on change in fair value of derivative liabilities						$ 400,000