X0306 4 2018-11-30 0 0000897448 AMARIN CORP PLC\UK AMRN 0001289884 Ketchum Steven B C/O AMARIN PHARMA, INC. 1430 ROUTE 206 BEDMINSTER NJ 07921 0 1 0 0 Chief Scientific Officer Ordinary Shares 2018-11-30 4 M 0 2604 1.40 A 343901 D Ordinary Shares 2018-11-30 4 M 0 4167 2.50 A 348068 D Ordinary Shares 2018-11-30 4 M 0 3750 2.50 A 351818 D Ordinary Shares 2018-11-30 4 M 0 3750 2.50 A 355568 D Ordinary Shares 2018-11-30 4 M 0 2771 2.95 A 358339 D Ordinary Shares 2018-11-30 4 S 0 17042 17.7898 D 341297 D Stock Option (Right to Buy) 1.40 2018-11-30 4 M 0 2604 0.00 D 2026-01-31 Ordinary Shares 2604 36458 D Stock Option (Right to Buy) 2.50 2018-11-30 4 M 0 4167 0.00 D 2025-07-06 Ordinary Shares 4167 29165 D Stock Option (Right to Buy) 2.50 2018-11-30 4 M 0 3750 0.00 D 2025-07-06 Ordinary Shares 3750 26250 D Stock Option (Right to Buy) 2.50 2018-11-30 4 M 0 3750 0.00 D 2025-07-06 Ordinary Shares 3750 56688 D Stock Option (Right to Buy) 2.95 2018-11-30 4 M 0 2771 0.00 D 2027-01-31 Ordinary Shares 2771 72540 D The option exercises and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person. The Ordinary Shares may be represented by American Depositary Shares, each of which currently represents one Ordinary Share. Please see the section titled "Remarks" below for additional information. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $17.12 to $18.04, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. On February 1, 2016, the Reporting Person was granted an option to purchase 125,000 Ordinary Shares under the Amarin Corporation plc 2011 Stock Incentive Plan (the "Plan"). The shares subject to this option shall vest and become exercisable in 48 equal monthly installments on the last day of each month that began on February 29, 2016. On July 6, 2015, the Reporting Person was granted an option to purchase 200,000 Ordinary Shares under the Plan. The shares subject to this option shall vest and become exercisable in 48 equal monthly installments on the last day of each month that began on July 31, 2015. On July 6, 2015, the Reporting Person was granted an option to purchase 180,000 Ordinary Shares under the Plan. The vesting of the shares is subject to certain performance milestone that was previously achieved. The shares subject to this option shall vest and become exercisable in 48 equal monthly installments on the last day of each month that began on July 31, 2015. On February 1, 2017, the Reporting Person was granted an option to purchase 133,000 Ordinary Shares under the Plan. The shares subject to this option shall vest and become exercisable in 48 equal monthly installments on the last day of each month that began on February 28, 2017. In the case of a Change of Control (as defined in the Plan), the grants described in this Form 4 vest in full. As of the date of this Form 4, the Reporting Person owns or holds the right to acquire an aggregate of 1,526,953 Ordinary Shares of the Issuer in the form of Ordinary Shares, and stock options and Restricted Stock Units granted under the Amarin Corporation plc 2002 Stock Option Plan and the Plan. /s/ Joseph T. Kennedy, by power of attorney 2018-11-30