X0306 4 2016-11-09 0 0000897448 AMARIN CORP PLC\UK AMRN 0001408920 Kennedy Joseph T C/O AMARIN PHARMA, INC. 1430 ROUTE 206 BEDMINSTER NJ 07921 0 1 0 0 General Counsel Ordinary Shares 2016-11-09 4 S 0 122358 3.0406 D 162120 D The Ordinary Shares may be represented by American Depositary Shares, each of which represents one Ordinary Share. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.00 to $3.10, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. Please see the section titled "Remarks" below for additional information. As of the date of this Form 4, the Reporting Person owns or holds the right to acquire an aggregate of 3,424,807 Ordinary Shares of the Issuer in the form of (i) stock options and Restricted Stock Units granted under the Amarin Corporation plc 2002 Stock Option Plan and the Amarin Corporation plc 2011 Stock Option Plan and (ii) 162,120 Ordinary Shares. /s/ Joseph T. Kennedy 2016-11-10