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Significant Accounting Policies - Calculation of Net Loss and Number of Shares Used to Compute Basic and Diluted Net Loss per Share (Detail) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Loss Earnings Per Share [Line Items]        
Net loss-basic and diluted $ (17,560) $ (69,956) $ (34,020) $ (101,519)
Weighted average shares outstanding-basic 407,848 398,187 407,017 397,997
Weighted average shares outstanding-diluted 407,848 398,187 407,017 397,997
Net loss per share basic [1] $ (0.04) $ (0.18) $ (0.08) $ (0.26)
Net loss per share-diluted [1] $ (0.04) $ (0.18) $ (0.08) $ (0.26)
[1] Excluding the licensing revenue change in estimate, as discussed in Note 8 - Development, Commercialization and Supply Agreements, net loss per share basic and diluted for the three and six months ended June 30, 2023 would have been $(0.06) and $(0.10), respectively.