Commitments and Contingencies - Additional Information (Detail) - Mar. 31, 2023 $ in Millions	USD ($)	GBP (£)
Commitments And Contingencies Disclosure [Line Items]
Future contractual purchase obligations without consideration	$ 81.7
Regulatory Approval in Europe
Commitments And Contingencies Disclosure [Line Items]
Additional future contractual purchase obligations without consideration	39.8
Further Indication for AMR101 | Potential Marketing Approval 1
Commitments And Contingencies Disclosure [Line Items]
Aggregate stock or cash payment upon potential market approval	5.5	£ 5,000,000
Further Indication for AMR101 | Potential Marketing Approval 2
Commitments And Contingencies Disclosure [Line Items]
Aggregate stock or cash payment upon potential market approval	$ 5.5	£ 5,000,000