Significant Accounting Policies (Tables)

3 Months Ended

Mar. 31, 2023

Accounting Policies [Abstract]

Summary of Impact of Accounts Receivable Reserves on Gross Trade Accounts Receivable Balances

The following table summarizes the impact of accounts receivable reserves on the gross trade accounts receivable balances as of March 31, 2023 and December 31, 2022:

In thousands	March 31, 2023			December 31, 2022
Gross trade accounts receivable	$	164,010		$	187,418
Trade allowances		(18,920	)		(44,626	)
Chargebacks		(11,854	)		(11,802	)
Accounts receivable, net	$	133,236		$	130,990

Calculation of Net Loss and Number of Shares Used to Compute Basic and Diluted Net Loss per Share

The calculation of net loss and the number of shares used to compute basic and diluted net loss per share for the three months ended March 31, 2023 and 2022 are as follows:

	For the Three Months Ended March 31,
In thousands	2023			2022
Net loss—basic and diluted	$	(16,460	)	$	(31,563	)
Weighted average shares outstanding—basic and diluted		406,177			397,805
Net loss per share—basic and diluted	$	(0.04	)	$	(0.08	)

Anti-Dilutive Securities Not Included in the Computation of Net Loss per Share

For the three months ended March 31, 2023 and 2022, the following potentially dilutive securities were not included in the computation of net loss per share because the effect would be anti-dilutive or because performance criteria were not yet met for awards contingent upon such measures:

	For the Three Months Ended March 31,
In thousands	2023		2022
Stock options		19,639		19,639
Restricted stock and restricted stock units		18,568		15,369
Laxdale milestone shares		—		1,984

Estimated Fair Value of Assets and Liability

The following tables present information about the estimated fair value of the Company’s assets and liabilities as of March 31, 2023 and December 31, 2022 and indicate the fair value hierarchy of the valuation techniques the Company utilized to determine such fair value:

	March 31, 2023
In thousands	Total		Level 1		Level 2		Level 3
Asset:
Agency Securities	$	3,999	$	3,999	$	—	$	—
Money Market Fund		80,105		80,105		—		—
U.S. Treasury Securities		3,153		3,153		—		—
Corporate Bonds		16,035		—		16,035		—
Commercial Paper		79,440		—		79,440		—
Repo Securities		3,250		—		3,250		—
Asset-Backed Securities		546		—		546		—
Certificate of Deposit		8,490		—		8,490		—
Non-US Government Securities		1,399		—		1,399		—
Total	$	196,417	$	87,257	$	109,160	$	-

	December 31, 2022
In thousands	Total		Level 1		Level 2		Level 3
Asset:
Money Market Fund	$	81,870	$	81,870	$	—	$	—
U.S. Treasury Securities		3,117		3,117		—		—
Agency Securities		1,554		1,554		—		—
Corporate Bonds		28,416		—		28,416		—
Commercial Paper		62,347		—		62,347		—
Repo Securities		3,250		—		3,250		—
Asset-Backed Securities		1,260		—		1,260		—
Certificate of Deposit		9,100		—		9,100		—
Non-US Government Securities		1,393		—		1,393		—
Total	$	192,307	$	86,541	$	105,766	$	—

Change in Restructuring Liability Associated with the Plan

The following table shows the change in restructuring liability which is included within accrued expenses and other current liabilities:

In thousands	Restructuring Liability
Balance at December 31, 2022	$	192
Costs incurred		12,254
Payments		(10,323	)
Balance at March 31, 2023	$	2,123