Income Taxes - Income Taxes Effect of Each Type of Temporary Difference Comprising Net Differed Tax Asset (Detail) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Deferred tax assets:
Net operating losses	$ 136,862	$ 127,378
Stock-based compensation	11,616	8,563
Tax credits	2,639	15,803
Capitalized R&D	4,723
Lease liability	2,583	2,348
Other reserves and accrued liabilities	11,895	11,257
Gross deferred tax assets	170,318	165,349
Less: valuation allowance	(165,378)	(160,295)	$ (160,841)
Total deferred tax assets	4,940	5,054
Deferred tax liabilities:
Depreciation and amortization	(3,337)	(3,404)
Lease asset	(1,603)	(1,639)
Other liabilities	0	(11)
Total deferred tax liabilities	(4,940)	(5,054)
Net deferred tax assets	$ 0	$ 0