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Stock Incentive Plans and Stock-Based Compensation - Additional Information (Detail)
6 Months Ended 12 Months Ended
Nov. 30, 2022
$ / shares
shares
May 31, 2022
$ / shares
shares
Nov. 30, 2021
$ / shares
shares
May 31, 2021
$ / shares
shares
Nov. 30, 2020
$ / shares
shares
May 31, 2020
$ / shares
shares
Dec. 31, 2022
USD ($)
$ / shares
Dec. 31, 2021
USD ($)
$ / shares
Dec. 31, 2020
USD ($)
$ / shares
Dec. 31, 2022
£ / shares
Dec. 31, 2022
USD ($)
shares
Dec. 31, 2021
£ / shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                        
Common stock, par value | £ / shares                   £ 0.50   £ 0.50
Weighted average fair value of the stock options granted | $ / shares             $ 2.56 $ 5.12 $ 14.43      
Grant date fair value of options vested             $ 16,600,000 $ 21,100,000 $ 22,500,000      
Proceeds from the exercise of options             $ 60,000 2,921,000 5,158,000      
Intrinsic value of options exercised               4,900,000 9,000,000.0      
Unrecognized stock-based compensation expense related to stock option                     $ 13,500,000  
Unrecognized stock-based compensation expense related to stock option, recognition period             2 years 1 month 6 days          
Compensation expense related to stock option             $ 14,800,000 23,000,000.0 22,400,000      
Compensation expense in relation to restricted stock units             $ 11,400,000 $ 13,900,000 $ 23,400,000      
Ordinary shares, reserved and available for issuance | shares                     15,383,000  
Stock Options                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                        
Employee Stock options, Vesting Period             4 years          
Restricted Stock Units (RSUs)                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                        
Unrecognized stock-based compensation expense related to stock option                     $ 23,700,000  
Unrecognized stock-based compensation expense related to stock option, recognition period             2 years 2 months 12 days          
Stock Incentive Plan 2020                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                        
Number of shares | shares                     20,000,000  
Plans | Stock Options                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                        
Employee Stock options, Vesting Period             4 years          
Expire period             10 years          
2017 Employee Stock Purchase Plan                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                        
Ordinary shares, reserved and available for issuance | shares                     3,000,000  
Percentage of fair market value to payroll deductions to eligible employees to purchase ordinary shares             85.00%          
Maximum fair market value of stock which can be purchased by participant in calendar year             $ 25,000          
Issuance of common stock under employee stock purchase plan (in shares) | shares 191,482 265,214 172,884 226,402 223,545 123,608            
Sale of stock price per share | $ / shares $ 1.15 $ 1.45 $ 3.06 $ 3.86 $ 4.22 $ 5.83            
Reserved for future issuance | shares                     1,361,577  
2017 Employee Stock Purchase Plan | Maximum                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                        
Percentage of payroll deductions to eligible employees to purchase ordinary shares                     15.00%