Revenue Recognition - Summarize Activity of the Net Product Revenue Allowance and Reserve Categories (Detail) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	$ 282,197	$ 190,827
Provision related to current period sales	584,945	627,571
Provision related to prior period sales	1,167	(854)
Credits/payments made for current period sales	(406,425)	(362,460)
Credits/payments made for prior period sales	(263,543)	(172,378)
Ending balance	198,341	282,706
Trade Allowances
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	86,636	36,242
Provision related to current period sales	71,164	90,761
Credits/payments made for current period sales	(26,746)	(27,635)
Credits/payments made for prior period sales	(83,398)	(34,511)
Ending balance	47,656	64,857
Rebates, Chargebacks and Discounts
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	184,726	141,201
Provision related to current period sales	490,995	497,726
Provision related to prior period sales	1,167	(854)
Credits/payments made for current period sales	(360,256)	(303,029)
Credits/payments made for prior period sales	(176,107)	(131,320)
Ending balance	140,525	203,724
Product Returns
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	8,090	7,797
Provision related to current period sales	1,738	2,647
Credits/payments made for prior period sales	(1,408)	(958)
Ending balance	8,420	9,486
Other Incentives
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	2,745	5,587
Provision related to current period sales	21,048	36,437
Credits/payments made for current period sales	(19,423)	(31,796)
Credits/payments made for prior period sales	(2,630)	(5,589)
Ending balance	$ 1,740	$ 4,639