Commitments and Contingencies - Additional Information (Detail) $ in Millions	Sep. 30, 2022 USD ($)	Sep. 30, 2022 GBP (£)	Jul. 13, 2022 GBP (£)	Mar. 26, 2021 GBP (£)
Commitments And Contingencies Disclosure [Line Items]
Future contractual purchase obligations without consideration | $	$ 81.5
Further Indication for AMR101 | Marketing Approval In Europe
Commitments And Contingencies Disclosure [Line Items]
Potential aggregate stock or cash payment				£ 7,500,000
Aggregate stock or cash payment upon potential market approval			£ 7,500,000
Further Indication for AMR101 | Potential Marketing Approval 1
Commitments And Contingencies Disclosure [Line Items]
Aggregate stock or cash payment upon potential market approval	5.5	£ 5,000,000
Further Indication for AMR101 | Potential Marketing Approval 2
Commitments And Contingencies Disclosure [Line Items]
Aggregate stock or cash payment upon potential market approval	$ 5.5	£ 5,000,000