Revenue Recognition - Summarize Activity of the Net Product Revenue Allowance and Reserve Categories (Detail) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	$ 280,693	$ 190,827
Provision related to current period sales	398,246	409,766
Provision related to prior period sales	107	(854)
Credits/payments made for current period sales	(271,693)	(212,807)
Credits/payments made for prior period sales	(214,794)	(168,242)
Ending balance	192,559	218,690
Trade Allowances
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	86,636	36,242
Provision related to current period sales	48,472	60,487
Credits/payments made for current period sales	(20,724)	(19,874)
Credits/payments made for prior period sales	(83,398)	(34,511)
Ending balance	30,986	42,344
Rebates, Chargebacks and Discounts
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	184,726	141,201
Provision related to current period sales	333,126	321,400
Provision related to prior period sales	107	(854)
Credits/payments made for current period sales	(237,768)	(170,389)
Credits/payments made for prior period sales	(128,152)	(127,379)
Ending balance	152,039	163,979
Product Returns
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	8,090	7,797
Provision related to current period sales	1,178	1,750
Credits/payments made for prior period sales	(614)	(763)
Ending balance	8,654	8,784
Other Incentives
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	1,241	5,587
Provision related to current period sales	15,470	26,129
Credits/payments made for current period sales	(13,201)	(22,544)
Credits/payments made for prior period sales	(2,630)	(5,589)
Ending balance	$ 880	$ 3,583