Revenue Recognition - Summarize Activity of the Net Product Revenue Allowance and Reserve Categories (Detail) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	$ 280,693	$ 190,827
Provision related to current period sales	179,774	191,325
Provision related to prior period sales	(301)	(854)
Credits/payments made for current period sales	(76,832)	(29,525)
Credits/payments made for prior period sales	(139,615)	(121,126)
Ending balance	243,719	230,647
Trade Allowances
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	86,636	36,242
Provision related to current period sales	22,697	29,134
Credits/payments made for current period sales	(2,753)	(3,582)
Credits/payments made for prior period sales	(13,536)	(7,086)
Ending balance	93,044	54,708
Rebates, Chargebacks and Discounts
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	184,726	141,201
Provision related to current period sales	148,203	148,241
Provision related to prior period sales	(301)	(854)
Credits/payments made for current period sales	(67,700)	(16,136)
Credits/payments made for prior period sales	(123,099)	(108,020)
Ending balance	141,829	164,432
Product Returns
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	8,090	7,797
Provision related to current period sales	549	828
Credits/payments made for prior period sales	(350)	(402)
Ending balance	8,289	8,223
Other Incentives
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	1,241	5,587
Provision related to current period sales	8,325	13,122
Credits/payments made for current period sales	(6,379)	(9,807)
Credits/payments made for prior period sales	(2,630)	(5,618)
Ending balance	$ 557	$ 3,284