Significant Accounting Policies (Tables)

3 Months Ended

Mar. 31, 2022

Accounting Policies [Abstract]

Summary of Impact of Accounts Receivable Reserves on Gross Trade Accounts Receivable Balances

The following table summarizes the impact of accounts receivable reserves on the gross trade accounts receivable balances as of March 31, 2022 and December 31, 2021:

In thousands	March 31, 2022			December 31, 2021
Gross trade accounts receivable	$	217,821		$	262,948
Trade allowances		(93,044	)		(86,636	)
Chargebacks		(13,598	)		(11,714	)
Allowance for doubtful accounts		(945	)		(945	)
Accounts receivable, net	$	110,234		$	163,653

Calculation of Net Loss and Number of Shares Used to Compute Basic and Diluted Net Loss per Share

The calculation of net loss and the number of shares used to compute basic and diluted net loss per share for the three months ended March 31, 2022 and 2021 are as follows:

	For the Three Months Ended March 31,
In thousands	2022			2021
Net loss—basic and diluted	$	(31,563	)	$	(1,626	)
Weighted average shares outstanding—basic and diluted		397,805			394,638
Net loss per share—basic and diluted	$	(0.08	)	$	(0.00	)

Anti-Dilutive Securities Not Included in the Computation of Net Loss per Share

For the three months ended March 31, 2022 and 2021, the following potentially dilutive securities were not included in the computation of net loss per share because the effect would be anti-dilutive or because performance criteria were not yet met for awards contingent upon such measures:

	For the Three Months Ended March 31,
In thousands	2022		2021
Stock options		19,639		19,372
Restricted stock and restricted stock units		15,369		10,252
Laxdale milestone shares		1,984		—

Estimated Fair Value of Assets and Liability

The following tables present information about the estimated fair value of the Company’s assets and liabilities as of March 31, 2022 and December 31, 2021 and indicate the fair value hierarchy of the valuation techniques the Company utilized to determine such fair value:

	March 31, 2022
In thousands	Total		Level 1		Level 2		Level 3
Asset:
Money Market Fund	$	129,031	$	129,031	$	—	$	—
U.S. Treasury Shares		7,219		7,219		—		—
Corporate Bonds		59,944		—		59,944		—
Commercial Paper		73,652		—		73,652		—
Repo Securities		4,750		—		4,750		—
Asset Backed Securities		6,707		—		6,707		—
Certificate of Deposit		24,603		—		24,603		—
Non-US Government		8,668		—		8,668		—
Total	$	314,574	$	136,250	$	178,324	$	—

	December 31, 2021
In thousands	Total		Level 1		Level 2		Level 3
Asset:
Money Market Fund	$	95,063	$	95,063	$	—	$	—
U.S. Treasury Shares		23,219		23,219		—		—
Corporate Bonds		83,587		—		83,587		—
Commercial Paper		121,773		—		121,773		—
Repo Securities		8,000		—		8,000		—
Asset Backed Securities		8,816		—		8,816		—
Certificate of Deposit		21,553		—		21,553		—
Non-US Government		12,900		—		12,900		—
Total	$	374,911	$	118,282	$	256,629	$	-

Change in Restructuring Liability Associated with the Plan

The following table shows the change in restructuring liability, associated with the Plan, which is included within accrued expenses and other current liabilities:

In thousands	Restructuring Liability
Balance at December 31, 2021	$	1,186
Payments		(948	)
Balance at March 31, 2022	$	238