Revenue Recognition - Summarize Activity of the Net Product Revenue Allowance and Reserve Categories (Detail) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2021	Jun. 30, 2020
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	$ 190,827	$ 128,557
Provision related to current period sales	409,766	361,984
Provision related to prior period sales	(854)	(3,872)
Credits/payments made for current period sales	(212,807)	(206,059)
Credits/payments made for prior period sales	(168,242)	(118,601)
Ending balance	218,690	162,009
Trade Allowances
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	36,242	29,261
Provision related to current period sales	60,487	59,829
Credits/payments made for current period sales	(19,874)	(23,197)
Credits/payments made for prior period sales	(34,511)	(29,067)
Ending balance	42,344	36,826
Rebates, Chargebacks and Discounts
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	141,201	90,997
Provision related to current period sales	321,400	266,823
Provision related to prior period sales	(854)	(3,872)
Credits/payments made for current period sales	(170,389)	(152,965)
Credits/payments made for prior period sales	(127,379)	(85,622)
Ending balance	163,979	115,361
Product Returns
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	7,797	4,579
Provision related to current period sales	1,750	1,589
Credits/payments made for prior period sales	(763)	(191)
Ending balance	8,784	5,977
Other Incentives
Valuation And Qualifying Accounts Disclosure [Line Items]
Beginning balance	5,587	3,720
Provision related to current period sales	26,129	33,743
Credits/payments made for current period sales	(22,544)	(29,897)
Credits/payments made for prior period sales	(5,589)	(3,721)
Ending balance	$ 3,583	$ 3,845