Exhibit 5.2 - Opinion of Kirkpatrick & Lockhart Nicholson Graham LLP

This Opinion is being delivered to you in connection with the proposed placement by the Company of 840,000 ordinary shares of £0.05 each in the capital of the Company (the "Shares") and the grant of warrants to subscribe for 294,000 ordinary shares of £0.05 each in the Company pursuant to the securities purchase agreement dated 23 January 2006 and entered into between the Company and Dr Anthony Ryan and the securities purchase agreement dated 23 January 2006 and entered into between the Company and Richard Strappe (together, the "Securities Purchase Agreements"). The Shares have not been registered under the United States Securities Act of 1933, as amended, and the rules and regulations thereunder with the United States Securities and Exchange Commission (the "SEC").

1.2

a certificate from the Company Secretary of the Company (the "Secretary's Certificate") of the same date as this Opinion confirming, inter alia, the amount of the Company's authorised but unissued share capital, the nominal amount of relevant securities which the directors are authorised to allot under section 80 of the UK Companies Act 1985 (as amended) (the "Act") and the extent of the powers to allot equity securities conferred on the directors under section 95 of the Act;

1.3	information on the file held at Companies House in respect of the Company disclosed by an online search carried out by us at Companies House at 3.00 pm on 25 January 2006;

1.4	a copy of the minutes of a meeting of the board of directors of the Company held on 23 January 2006 a copy of which is attached to the Secretary's Certificate;

but in relation to 1.6 above, for the sole limited purpose of this Opinion and specifically not in relation to compliance with the laws of the United States or any State or jurisdiction thereof, the rules of any non-UK regulatory body (including without limitation, the SEC), any securities exchange (including without limitation, NASDAQ) or matters of fact.

2.1	the authenticity, accuracy and completeness of all documents submitted to us as originals or copies, the genuineness of all signatures and the conformity to original documents of all copies;

2.3	the due execution and delivery of any documents reviewed by us in compliance with all requisite corporate authorisations (other than the execution by the Company of the Securities Purchase Agreements);

2.5	that the contents of the Secretary's Certificate were true when given and remain true and that there is no matter not referred to in that Certificate which would make any of the information in the Secretary's Certificate incorrect or misleading;

2.7

that, having undertaken such Companies House search and a winding up search at the Companies Court in England on 26 January 2006 and having made enquiries of the Company Secretary (the "Searches and Enquiries") (but having made no other searches or enquiries) and the Searches and Enquiries not revealing any of the same, no members' or creditors' voluntary winding up resolution has been passed and no petition has been presented and no order has been made for the administration, winding up or dissolution of the Company and no receiver, administrative receiver, administrator or similar officer has been appointed in relation to the Company or any of its assets;

(a)	no alteration shall have been made as at the date of allotment of the Shares to either the memorandum of association or the articles of association of the Company;

(b)	as at the date of allotment of such Shares, the number of Shares to be allotted shall fall within the authorised and unallotted share capital of the Company; and

(c)

at the time of issue of the Shares the Company shall have received in full in cash the subscription price payable for the Shares and shall have entered the holder or holders thereof in the register of members of the Company showing that all the Shares shall have been fully paid up as to their nominal value and any premium thereon as at the date of their allotment;

(a)	(which is confirmed by the Secretary's Certificate) a meeting of the board of directors of the Company (or a duly constituted and empowered committee thereof) shall have been duly convened and held and a valid resolution passed at such meeting to approve the allotment and issue of the Shares;

(b)

(which is confirmed by the Secretary's Certificate) as at the date of allotment of the Shares, the directors of the Company shall have sufficient powers conferred on them to allot the Shares under section 80 of the Act and under section 95 of the Act as if section 89(1) of the Act did not apply to such allotment;

(c)	that the directors will use all their authorities and exercise all their powers in connection with the allotment and issue of the Shares and setting the subscription price in each case bona fide in the interests of the Company;

(e)	in the event that the Shares are allotted at a price per share which is less than the then current market price for the Shares on the Nasdaq Stock Market, the issue price will be a fair price which is reasonable in all the circumstances;

2.10	that the Shares shall not be offered to the public in the United Kingdom in breach of any UK laws or regulations concerning the offer of securities to the public;

2.11

that no Shares shall be issued such that any person, or persons acting in concert, whether in one or more transactions and whether or not aggregated with any existing holding, shall acquire shares in the Company carrying 30 per cent or more of the voting rights of the Company or otherwise to be required to make a mandatory offer under Rule 9 of the City Code on Takeovers and Mergers;

2.13	that no shares or securities in the Company are listed on any recognised investment exchange in the United Kingdom (as defined in section 285 of the Financial Services and Markets Act 2000).

(a)	the Company is duly incorporated and validly existing as a public limited company in good standing under the laws of England and Wales, with corporate power and authority to conduct business and to execute the Securities Purchase Agreements and to allot and issue the Shares as described therein;

(b)	each of the Securities Purchase Agreements has been duly authorised, executed and delivered by the Company. Such execution of the Securities Purchase Agreements by the Company will not conflict with the memorandum and articles of association of the Company, nor with the laws of England and Wales;

(c)

upon payment therefor, the Shares will have been duly authorised and validly issued and will be fully paid and non-assessable. For the purposes of this opinion, we have assumed the term "non-assessable" in relation to the Shares means under English law that holders of such Shares, in respect of which all amounts due on such Shares as to the nominal amount and any premium thereon have been fully paid, will be under no obligation to contribute to the liabilities of the Company solely in their capacity as holders of such Shares; and

(d)	no further approval of the shareholders of the Company is required in connection with the allotment and issue of the Shares and the performance by the Company of the Securities Purchase Agreements.

4.1

we express no opinion as to any law other than English law in force, and as interpreted, at the date of this Opinion. We are not qualified to, and we do not, express an opinion on the laws of any other jurisdiction. In particular and without prejudice to the generality of the foregoing, we have not independently investigated the laws of the United States of America or the State of New York or the rules of any non-UK regulatory body (including without limitation, the SEC) or any securities exchange (including without limitation, NASDAQ) for the purpose of this Opinion;

4.2	this Opinion deals exclusively with the statutory authorities and powers required by the directors of the Company to allot the Shares and not with any contractual restrictions which may be binding on the Company or its directors or any investing institutions' guidelines;

4.3	the information contained in searches obtained from the Registrar of Companies is not always up to date or complete as a result of inaccuracies or delays in filing by the persons responsible and/or misfiling or delays by staff at Companies House;

4.4

the list of members maintained by the Company's registrar does not disclose details of the payment up of any Shares, such details being recorded by the Company in a separate register of allotments which contains certain of the information required under the Act and we assume that the same procedure will be adopted in relation to the Shares; and

This Opinion speaks only as at the date hereof. Notwithstanding any reference herein to future matters or circumstances, we have no obligation to advise the addressee (or any third party) of any changes in the law or facts that may occur after the date of this Opinion.

This Opinion is given on condition that it is governed by and shall be construed in accordance with English law in force and interpreted at the date of this Opinion. We have not investigated the laws of any country other than England and Wales.

This Opinion is given solely to you for the purpose of the Securities Purchase Agreements. It may not be used nor relied upon for any other purpose or by any other person. We are acting solely for the Company in relation to the Securities Purchase Agreements and we do not owe any duty to, or accept any liability to, any other person except that the other named addressees of this letter shall be entitled to rely on this Opinion.

Purchaser:	Address:
Dr Anthony Ryan	Park Place, Block B, 6 Impasse De La Fontane, Monte Carlo, 9800 Monaco Ville
Mr Richard Strapple	Mount Judkin, Cashel, Co. Tipperary, Republic of Ireland