LETTER 1 filename1.txt Via Facsimile and U.S. Mail Mail Stop 6010 October 28, 2005 Richard Stewart Chief Executive Officer Amarin Corporation plc 7 Curzon Street London W1J 5HG England Re: Amarin Corporation plc Form 20-F for the fiscal year ended December 31, 2004 Filed April 1, 2005 File No. 000-21392 Dear Mr. Stewart: We have completed our review of your Form 20-F and related filings and have no further comments at this time. Sincerely, Kevin Woody Accounting Branch Chief