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CONDENSED CONSOLIDATED STATEMENT OF CHANGES IN STOCKHOLDERS' EQUITY (Unaudited) - USD ($)
Preferred Stock [Member]
Common Stock [Member]
Additional Paid-In Capital [Member]
Accumulated Deficit [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Non-Controlling Interest [Member]
Total
Balance at Dec. 31, 2017 $ 479 $ 1,511 $ 36,916,659 $ (23,414,151) $ 4,503,046 $ 780,737 $ 18,788,281
Balance (in shares) at Dec. 31, 2017 478,776 1,511,115          
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Compensation expense due to stock option issuances 232,854 232,854
Compensation expense due to warrant issuances 23,477 23,477
Issuance of common stock and warrants for cash $ 256 6,243,099 6,243,355
Issuance of common stock and warrants for cash (in shares) 256,040          
Issuance of common stock for services $ 84 3,033,212 3,033,296
Issuance of common stock for services (in shares) 84,152          
Issuance of common stock for conversion of debt $ 102 2,167,742 2,167,844
Issuance of common stock for conversion of debt (in shares) 101,500          
Issuance of common stock upon exercise of stock options $ 3 97,797 97,800
Issuance of common stock upon exercise of stock options (in shares) 3,000          
Issuance of common stock upon exercise of warrants $ 93 867,073 867,166
Issuance of common stock upon exercise of warrants (in shares) 93,323          
Issuance of common stock for conversion of Series E preferred stock $ (254) $ 26 (26)
Issuance of common stock for conversion of Series E preferred stock (in shares) (254,500) 25,450          
Issuance of common stock in connection with convertible notes $ 27 353,646 353,673
Issuance of common stock in connection with convertible notes (in shares) 27,173          
Beneficial conversion feature in connection with convertible notes 288,573 288,573
Fair value of warrants issued in connection with convertible notes 1,405,048 1,405,048
Cash for exchange fees and other financing costs (858,671) (858,671)
Comprehensive loss:              
Net loss (6,060,522) (6,060,522)
Net unrealized gain on securities available-for-sale, net of income taxes (4,741,114) (4,741,114)
Foreign currency translation adjustments         26,457 26,457
Net loss attributable to non-controlling interest           (35,431) (35,431)
Balance at Mar. 31, 2018 $ 225 $ 2,102 50,770,483 (29,474,673) (211,611) 745,306 21,832,086
Balance (in shares) at Mar. 31, 2018 224,276 2,101,753          
Balance at Dec. 31, 2018 $ 126 $ 4,036 77,643,609 (55,721,115) (3,902,523) 40,658 18,064,791
Balance (in shares) at Dec. 31, 2018 126,434 4,036,407          
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Compensation expense due to stock option issuances 245,614 245,614
Issuance of common stock and warrants for cash $ 3,792 4,393,743 4,397,535
Issuance of common stock and warrants for cash (in shares) 3,791,642          
Issuance of common stock for services $ 375 252,644 253,019
Issuance of common stock for services (in shares) 375,000          
Issuance of common stock for conversion of debt $ 1,056 2,607,401 2,608,457
Issuance of common stock for conversion of debt (in shares) 1,056,066          
Issuance of Series A preferred stock for cash 1,750 1,750
Issuance of Series A preferred stock for cash (in shares) 70          
Cash for exchange fees and other financing costs (250,141) (250,141)
Comprehensive loss:              
Net loss (6,678,610) (6,678,610)
Preferred deemed dividends (1,869) (1,869)
Net unrealized loss on derivatives in related party (736,680) (736,680)
Foreign currency translation adjustments       131,130 29,857   29,857
Net loss attributable to non-controlling interest           (32,416) (32,416)
Balance at Mar. 31, 2019 $ 126 $ 9,259 $ 84,894,620 $ (62,270,464) $ (4,609,346) $ 8,242 $ 18,032,437
Balance (in shares) at Mar. 31, 2019 126,504 9,259,115