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DESCRIPTION OF BUSINESS (Details) - USD ($)
$ in Thousands
Jun. 30, 2022
Dec. 31, 2021
Description of Business and Basis of Presentation [Line Items]    
Accumulated deficit $ (620,571) $ (605,643)
Cash and cash equivalents 18,862 $ 38,704
CASI China    
Description of Business and Basis of Presentation [Line Items]    
Cash and cash equivalents $ 13,400