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Share-Based Compensation (Details) (USD $)
3 Months Ended 6 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Jun. 30, 2012
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Research and development $ 836,582 $ 696,287 $ 1,342,957 $ 1,257,536
General and administrative 1,015,701 601,502 1,645,603 1,698,248
Share-based compensation expense     1,164,578 468,353
Compensation Expense [Member]
       
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Research and development     465,353 92,126
General and administrative     699,225 376,227
Share-based compensation expense     $ 1,164,578 $ 468,353
Net share-based compensation expense, per common share:        
Basic and diluted (in dollars per share)     $ 0.05 $ 0.03