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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
CASH FLOWS FROM OPERATING ACTIVITIES    
Net loss $ (33,487) $ (33,080)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization for property and equipment 389 561
Net loss on disposal of property and equipment 0 1
Amortization of intangible assets 1,095 1,182
Reduction in the carrying amount of the right-of-use assets 973 742
(Gain) loss on disposal of intangible assets (450) 48
Impairment of intangible assets 1,537 0
Stock-based compensation expense 5,685 5,320
Acquired in-process research and development 11,943 5,849
Change in fair value of investment in equity securities (2,287) 355
Non-cash interest 0 1
Changes in operating assets and liabilities:    
Accounts receivable (2,785) (2,643)
Inventories 3,822 (2,282)
Prepaid expenses and other assets (434) 2,796
Accounts payable (2,434) 3,877
Accrued liabilities and other liabilities (1,398) (1,152)
Deferred income (23) 0
Net cash used in operating activities (17,854) (18,425)
CASH FLOWS FROM INVESTING ACTIVITIES    
Proceeds from disposal of intangible assets 1,700 0
Purchases of property and equipment (367) (390)
Loan to a related party (10,033) 0
Receipt of repayment of loan from a related party 10,033 0
Cash paid for acquired in-process research and development (11,678) (5,849)
Cash paid to acquire equity securities in Black Belt Tx Limited 0 (2,250)
Cash paid to acquire debt securities in Black Belt Tx Limited (83) 0
Cash paid to acquire equity securities in Juventas Cell Therapy Ltd   (11,788)
Receipt of government grants related to land use right 2,278 0
Net cash used in investing activities (8,150) (20,277)
CASH FLOWS FROM FINANCING ACTIVITIES    
Proceeds from note payable 466  
Repayment of notes payable   (1,500)
Stock issuance costs (2,800) (8)
Proceeds from issuance of common stock 45,099 0
Cash contribution from redeemable noncontrolling interest 0 20,000
Proceeds from exercise of stock options 3,874 114
Repurchase of stock options to satisfy tax withholding obligations (251) (12)
Proceeds from exercise of warrants 0 1,668
Payment of deferred offfering costs 0 (369)
Net cash provided by financing activities 46,388 19,893
Effect of exchange rate change on cash and cash equivalents 587 (2,155)
Net increase (decrease) in cash and cash equivalents 20,971 (20,964)
Cash and cash equivalents at beginning of period 53,621 84,205
Cash and cash equivalents at end of period 74,592 63,241
Supplemental disclosure of cash flow information:    
Interest paid 0 30
Income taxes paid $ 0 $ 0