-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 MkJNAfTh8xn8solwmHSvP4q6zGCkhjAoRJaXCtCJdObEw+jmdhaOUK/c8Ry5ZnHh
 4vFKKWHxwwPY3iMBf6xhew==

<SEC-DOCUMENT>0001437749-10-001933.txt : 20100623
<SEC-HEADER>0001437749-10-001933.hdr.sgml : 20100623
<ACCEPTANCE-DATETIME>20100623140054
ACCESSION NUMBER:		0001437749-10-001933
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100622
FILED AS OF DATE:		20100623
DATE AS OF CHANGE:		20100623

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			RYDZEWSKI JOHN J
		CENTRAL INDEX KEY:			0001073168

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-20970
		FILM NUMBER:		10912356

	MAIL ADDRESS:	
		STREET 1:		C/O ARV ASSISTED LIVING INC
		STREET 2:		245 FISCHER AVE SUITE D-1
		CITY:			COSTA MESA
		STATE:			CA
		ZIP:			92626

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VISION SCIENCES INC /DE/
		CENTRAL INDEX KEY:			0000894237
		STANDARD INDUSTRIAL CLASSIFICATION:	ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS [3845]
		IRS NUMBER:				133430173
		STATE OF INCORPORATION:			NY
		FISCAL YEAR END:			0331

	BUSINESS ADDRESS:	
		STREET 1:		40 RAMLAND ROAD SOUTH
		CITY:			ORANGEBURG
		STATE:			NY
		ZIP:			10962
		BUSINESS PHONE:		845-365-0600

	MAIL ADDRESS:	
		STREET 1:		40 RAMLAND ROAD SOUTH
		CITY:			ORANGEBURG
		STATE:			NY
		ZIP:			10962
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rdgdoc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-06-22</periodOfReport>

    <issuer>
        <issuerCik>0000894237</issuerCik>
        <issuerName>VISION SCIENCES INC /DE/</issuerName>
        <issuerTradingSymbol>VSCI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001073168</rptOwnerCik>
            <rptOwnerName>RYDZEWSKI JOHN J</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O VISION-SCIENCES, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>40 RAMLAND ROAD SOUTH, SUITE 1</rptOwnerStreet2>
            <rptOwnerCity>ORANGEBURG</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10962</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock $0.01 Par Value per Share</value>
            </securityTitle>
            <transactionDate>
                <value>2010-06-22</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2010-06-22</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>2500.0000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.0074</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>22500.0000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>/s/ John J. Rydzewski</signatureName>
        <signatureDate>2010-06-23</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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