<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-10-14</periodOfReport>

    <notSubjectToSection16>1</notSubjectToSection16>

    <issuer>
        <issuerCik>0000894237</issuerCik>
        <issuerName>VISION SCIENCES INC /DE/</issuerName>
        <issuerTradingSymbol>VSCI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001387779</rptOwnerCik>
            <rptOwnerName>Cohen Yoav M</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O VISION-SCIENCES, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>40 RAMLAND ROAD SOUTH, SUITE 1</rptOwnerStreet2>
            <rptOwnerCity>ORANGEBURG</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10962</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Consultant ( Former CFO )</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <remarks>Mr. Yoav M. Cohen is no longer an employee or officer of Vision-Sciences, Inc. (the &quot;Company&quot;).  Although Mr. Cohen will continue to provide services to the Company as a consultant pursuant to a consulting agreement between Mr. Cohen and the Company executed on October 14, 2008, he will not be serving in a capacity that would render him a Section 16 filer under the Securities Exchange Act of 1934, as amended.</remarks>

    <ownerSignature>
        <signatureName>/s/ Yoav M. Cohen</signatureName>
        <signatureDate>2008-10-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
