SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
GLEESON CHRISTOPHER M

(Last) (First) (Middle)
1910 E. INNOVATION PARK DR

(Street)
TUCSON AZ 85755

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
VENTANA MEDICAL SYSTEMS INC [ VMSI ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
X Officer (give title below) Other (specify below)
President & CEO
3. Date of Earliest Transaction (Month/Day/Year)
02/07/2008
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 02/07/2008 M 5,728 A $89.4 95,812(1) D
Common Stock 02/07/2008 M 29,098 A $89.4 124,910 D
Common Stock 02/07/2008 M 32,000 A $89.4 156,910 D
Common Stock 02/07/2008 M 9,250 A $89.4 166,160 D
Common Stock 02/07/2008 M 20,000 A $89.4 186,160 D
Common Stock 02/07/2008 M 68,834 A $89.4 254,994 D
Common Stock 02/07/2008 M 32,854 A $89.4 287,848 D
Common Stock 02/07/2008 M 63,062 A $89.4 350,910 D
Common Stock 02/07/2008 M 84,934 A $89.4 435,844 D
Common Stock 02/07/2008 M 48,000 A $89.4 483,844 D
Common Stock 02/07/2008 M 10,000 A $89.4 493,844 D
Common Stock 02/07/2008 M 10,000 A $89.4 503,844 D
Common Stock 02/07/2008 M 10,000 A $89.4 513,844 D
Common Stock 02/07/2008 M 10,000 A $89.4 523,844 D
Common Stock 02/07/2008 M 10,000 A $89.4 533,844 D
Common Stock 02/07/2008 M 11,000 A $89.4 544,844 D
Common Stock 02/07/2008 M 11,000 A $89.4 555,844 D
Common Stock 02/07/2008 M 11,000 A $89.4 566,844 D
Common Stock 02/07/2008 M 11,000 A $89.4 577,844 D
Common Stock 02/07/2008 M 11,000 A $89.4 588,844 D
Common Stock 02/07/2008 M 1,801 A $89.4 590,645 D
Common Stock 02/07/2008 M 182 A $89.4 590,827 D
Common Stock 02/07/2008 M 11,172 A $89.4 601,999 D
Common Stock 02/07/2008 M 2,990 A $89.4 604,989 D
Common Stock 02/07/2008 M 1,400 A $89.4 606,389 D
Common Stock 02/07/2008 U 602,005 D $89.5 4,384 D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Options (Right to Buy) $8.938 02/07/2008 M 5,728 03/01/2000(2) 01/26/2009 Common Stock 5,728 $8.938 0 D
Stock Options (Right to Buy) $8.75 02/07/2008 M 29,098 01/31/2000(2) 04/12/2009 Common Stock 29,098 $8.75 0 D
Stock Options (Right to Buy) $11.75 02/07/2008 M 32,000 01/01/2001(3) 01/01/2010 Common Stock 32,000 $11.75 0 D
Stock Options (Right to Buy) $11.75 02/07/2008 M 9,250 01/24/2000 01/24/2010 Common Stock 9,250 $11.75 0 D
Stock Options (Right to Buy) $10.06 02/07/2008 M 20,000 02/01/2002(4) 01/22/2012 Common Stock 20,000 $10.06 0 D
Stock Options (Right to Buy) $10.06 02/07/2008 M 68,834 01/22/2003(3) 01/22/2013 Common Stock 68,834 $10.06 0 D
Stock Options (Right to Buy) $10.12 02/07/2008 M 32,854 01/27/2003 01/27/2013 Common Stock 32,854 $10.12 0 D
Stock Options (Right to Buy) $10.12 02/07/2008 M 63,062 01/27/2004(3) 01/27/2013 Common Stock 63,062 $10.12 0 D
Stock Options (Right to Buy) $22.365 02/07/2008 M 84,934 01/26/2004 01/26/2014 Common Stock 84,934 $22.365 0 D
Stock Options (Right to Buy) $22.365 02/07/2008 M 48,000 01/26/2005(3) 01/26/2014 Common Stock 48,000 $22.365 12,000 D
Stock Options (Right to Buy) $33.73 02/07/2008 M 10,000 12/28/2004 12/28/2014 Common Stock 10,000 $33.73 0 D
Stock Options (Right to Buy) $35.42 02/07/2008 M 10,000 02/28/2004 02/28/2014 Common Stock 10,000 $35.42 0 D
Stock Options (Right to Buy) $37.19 02/07/2008 M 10,000 12/28/2004 12/28/2014 Common Stock 10,000 $37.19 0 D
Stock Options (Right to Buy) $39.05 02/07/2008 M 10,000 12/28/2004 12/28/2014 Common Stock 10,000 $39.05 0 D
Stock Options (Right to Buy) $41 02/07/2008 M 10,000 12/28/2004 12/28/2014 Common Stock 10,000 $41 0 D
Stock Options (Right to Buy) $42.41 02/07/2008 M 11,000 12/15/2005 12/15/2015 Common Stock 11,000 $42.41 0 D
Stock Options (Right to Buy) $44.43 02/07/2008 M 11,000 12/15/2005 12/15/2015 Common Stock 11,000 $44.43 0 D
Stock Options (Right to Buy) $46.45 02/07/2008 M 11,000 12/15/2005 12/15/2015 Common Stock 11,000 $46.45 0 D
Stock Options (Right to Buy) $48.47 02/07/2008 M 11,000 12/15/2005 12/15/2015 Common Stock 11,000 $48.47 0 D
Stock Options (Right to Buy) $50.49 02/07/2008 M 11,000 12/15/2005 12/15/2015 Common Stock 11,000 $50.49 0 D
Stock Options (Right to Buy) $35.95 02/07/2008 M 1,801 03/03/2006 03/03/2016 Common Stock 1,801 $35.95 0 D
Stock Options (Right to Buy) $40.25 02/07/2008 M 182 03/28/2007(5) 02/28/2017 Common Stock 182 $40.25 11,512 D
Stock Options (Right to Buy) $40.25 02/07/2008 M 11,172 03/28/2007(5) 02/28/2017 Common Stock 11,172 $40.25 39,062 D
Stock Options (Right to Buy) $39.4 02/07/2008 M 2,990 03/02/2007 03/02/2017 Common Stock 2,990 $39.4 0 D
Stock Options (Right to Buy) $41.8 02/07/2008 M 1,400 04/02/2008(6) 04/02/2017 Common Stock 1,400 $41.8 280 D
Explanation of Responses:
1. Includes 30 shares acquired in February 2008 under Ventana's Employee Stock Purchase Plan
2. Stock options vest 14.28% after 12 months and 1/84th of the shares vest the last day of each month thereafter.
3. Stock options vest 20% after one year and 1/60th each month thereafter.
4. Stock options vest in 48 equal monthly installments.
5. Stock options vest in 60 equal monthly installments.
6. Stock options vest in 12 equal monthly installments.
Leslie Oaks, Attorney in Fact for Christopher Gleeson 02/07/2008
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.