X0101 EFFECT 33 LIVE 2018-04-30 16:30:00

N-4

0000892566 GENERAL AMERICAN SEPARATE ACCOUNT TWENTY-EIGHT 333-224517 S000004949 GENERAL AMERICAN SEPARATE ACCOUNT TWENTY-EIGHT C000013365 GENERAL AMERICAN SEPARATE ACCOUNT TWENTY-EIGHT S000004949 GENERAL AMERICAN SEPARATE ACCOUNT TWENTY-EIGHT C000202487 GenAm SA 28