Condensed Consolidated Statements of Operations (Unaudited) (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2013	Mar. 31, 2012
Revenues:
Product sales, net	$ 1,126
Total revenues	1,126
Operating costs and expenses:
Cost of product sold	55
Research and development	8,355	8,170
Selling, general and administrative	11,143	9,928
Total operating expenses	19,553	18,098
Loss from operations	(18,427)	(18,098)
Other income (expense):
Investment and other income (expense), net	(367)	190
Interest expense	(48)	(5)
Amortization of debt discount and issuance costs	(23)
Foreign exchange gain (loss)	(751)	384
Total other income (expense), net	(1,189)	569
Net loss before noncontrolling interest	(19,616)	(17,529)
Noncontrolling interest	232	83
Net loss	$ (19,384)	$ (17,446)
Basic and diluted net loss per common share	$ (0.18)	$ (0.43)
Shares used in calculation of basic and diluted net loss per common share	106,697	40,792