X0306 4 2020-07-01 0 0000891293 CTI BIOPHARMA CORP CTIC 0001339498 Craig Adam R 3101 WESTERN AVENUE, SUITE 800 SEATTLE WA 98121 1 1 0 0 President and CEO Common Stock 2020-07-01 4 A 0 5000 0.98 A 5000 D Stock Option (right to buy) 3.30 2021-03-10 4 A 0 800000 0.00 A 2031-03-10 Common Stock 800000 800000 D Shares acquired under the CTI BioPharma Corp. 2007 Employee Stock Purchase Plan. The stock option will vest in six equal semi-annual installments over a three-year period, subject to continued employment with the Company through the applicable vesting dates. The stock option is also subject to stockholder approval of an increase in the share reserve under the Company's 2017 Equity Incentive Plan, which approval must occur within one year from the grant date. /s/ Bruce J. Seeley, attorney-in-fact for Adam R. Craig 2021-03-12