X0306 4 2017-06-05 0 0000891293 CTI BIOPHARMA CORP CTIC 0001451935 Parkinson David Ross C/O CTI BIOPHARMA CORP. 3101 WESTERN AVE., SUITE 600 SEATTLE WA 98121 1 0 0 0 Stock Option (Right to Buy) 4.07 2017-06-05 4 A 0 50000 0.00 A 2027-06-05 Common Stock 50000 50000 D The stock options will vest on the first to occur of (1) June 5, 2018, (2) immediately prior to the first annual meeting of the Company's shareholders that occurs in 2018 and at which one or more members of the Board are to be elected, or (3) immediately prior to the occurrence of a Change in Control (as such term is defined in the 2017 Equity Incentive Plan), subject to Dr. Parkinson's continued service through such date or event. /s/ Bruce J. Seeley, Attorney-in-fact for David Parkinson 2017-06-07