X0306 4 2016-10-20 0 0000891293 CTI BIOPHARMA CORP CTIC 0001201041 LOVE RICHARD L 3101 WESTERN AVENUE, SUITE 600 SEATTLE WA 98121 1 1 0 0 Interim CEO and President Employee Stock Option (Right to Buy) 0.4087 2016-10-20 4 A 0 500000 0.00 A 2026-10-20 Common Stock 500000 500000 D Employee Stock Option (Right to Buy) 0.4087 2016-10-20 4 A 0 500000 0.00 A 2026-10-20 Common Stock 500000 500000 D The option is scheduled to vest in six monthly installments following the grant date, subject to the reporting person's continued employment with the issuer through the applicable vesting date. The option is scheduled to vest in six monthly installments following the grant date, subject to the reporting person's continued employment with the issuer through the applicable vesting date, and provided that a specified performance objective is achieved prior to October 2, 2018. /s/ Louis A. Bianco, attorney-in-fact for Richard L. Love 2016-10-24