X0306 4 2020-03-11 0 0000891293 CTI BIOPHARMA CORP CTIC 0001511051 Tuckson Reed Vaughn 3101 WESTERN AVENUE SUITE 800 SEATTLE WA 98121 1 0 0 0 Non-qualified Stock Option 1 2020-03-11 4 A 0 126000 0 A 2030-03-11 Common stock 126000 126000 D This stock option was granted on March 11, 2020 and vests on the first to occur of (i) the date that is twelve months after the date of grant, and (ii) immediately prior to the first annual meeting of the Company's stockholders in 2021 at which one or more members of the Company's Board of Directors are to be elected, subject to the Reporting Person's continued service through such date or event. The stock option is subject to stockholder approval of an increase in the share reserve under the 2017 Equity Incentive Plan of the Company, which approval must occur within one year from the grant date. /s/ Adam R. Craig, attorney-in-fact for Reed V. Tuckson 2020-03-13