X0306 4 2020-03-11 0 0000891293 CTI BIOPHARMA CORP CTIC 0001339498 Craig Adam R 3101 WESTERN AVENUE SUITE 800 WA 98121 1 1 0 0 President and CEO Non-qualified Stock Option 1 2020-03-11 4 A 0 2320000 0 A 2030-03-11 Common stock 2320000 2320000 D The stock option will vest in six equal semi-annual installments over a three-year period, subject to continued employment with the Company through the applicable vesting dates. The stock option is also subject to stockholder approval of an increase in the share reserve under the 2017 Equity Incentive Plan of the Company, which approval must occur within one year from the grant date. /s/ Adam R. Craig 2020-03-13