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Income Taxes - Reconciliation Between Effective and Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Income Tax Disclosure [Abstract]    
Federal income tax rate 21.00% 34.00%
Research and development tax credits 6.00% 3.00%
Non-deductible executive compensation (1.00%) 0.00%
Valuation allowance (12.00%) 304.00%
Impact of tax reform 0.00% (101.00%)
Expired tax attribute carryforwards (17.00%) (240.00%)
Gain on branch liquidation 3.00% 0.00%
Foreign currency gains and losses 2.00% 0.00%
Other (2.00%) 0.00%
Net effective tax rate 0.00% 0.00%