Collaboration, Licensing and Milestone Agreements (Tables)

12 Months Ended

Dec. 31, 2018

Collaborations [Abstract]

Allocation of Arrangement Consideration

At the inception of the Restated Agreement, the arrangement consideration of $12.8 million (€12.0 million converted into U.S. dollars using the currency exchange rate as of the date of the Restated Agreement) was included in the initial transaction price, which was then allocated based on the percentage of the relative selling price of each performance obligation as follows (in thousands):

License	$	11,487
Development and other services	1,348
Total upfront payment	$	12,835