X0306 4 2018-05-17 0 0000891293 CTI BIOPHARMA CORP ctic 0001511051 Tuckson Reed Vaughn 3101 WESTERN AVENUE SUITE 800 SEATTLE WA 98121 1 0 0 0 Non-Qualified Stock Option (right to buy) 4.61 2018-05-17 4 A 0 60000 0 A 2028-05-17 Common Stock 60000 60000 D This stock option was granted on May 17, 2018 and vests on the first to occur of (i) the date that is twelve months after the date of grant, and (ii) immediately prior to the first annual meeting of the Company's stockholders in 2019 at which one or more members of the Company's Board of Directors are to be elected, subject to the Reporting Person's continued service through such date or event. Bruce J. Seeley, Attorney-in-fact For: Reed V. Tuckson 2018-05-17