X0306 4 2018-05-16 0 0000891293 CTI BIOPHARMA CORP ctic 0001339498 Craig Adam R 3101 WESTERN AVENUE SUITE 800 SEATTLE WA 98121 1 1 0 0 President and CEO Non-Qualified Stock Option (right to buy) 4.14 2018-05-16 4 A 0 475000 0 A 2028-05-16 Common Stock 475000 475000 D The stock option will vest in six equal semi-annual installments over a three-year period commencing on March 9, 2018 subject to continued employment with the Company through the applicable vesting dates, such that the option will be fully vested on March 9, 2021. Bruce J. Seeley, Attorney-in-fact For: Adam R. Craig 2018-05-17