X0306 4 2015-12-23 0 0000891293 CTI BIOPHARMA CORP ctic 0001198554 BIANCO JAMES A 3101 WESTERN AVENUE SUITE 600 SEATTLE WA 98121 1 1 0 0 President and CEO Common Stock 2015-12-23 4 D 0 583217 0 D 2368302 D Employee Stock Option (Right to Buy) 1.24 2015-12-23 4 A 0 6000000 0 A 2025-12-23 Common Stock 6000000 6000000 D Represents the forfeiture back to CTIC of shares of restricted stock. The restricted shares were originally issued pursuant to a performance-based equity award effective as of January 3, 2012 and subsequently amended. The reporting person agreed to forfeit the restricted shares to the issuer. If a performance goal that had been applicable to such restricted stock is achieved by December 31, 2016, the reporting person will be entitled to the grant of a stock option from CTIC with respect to the same number of shares that would have been issued to the reporting person upon achievement of the goal under the original terms of the reporting person's long-term incentive award. The option is scheduled to vest in eight semi-annual installments over the four-year period following the grant date, subject to the reporting person's continued employment or service with the issuer through the applicable vesting date. By: Louis A. Bianco, Attorney-in-fact For: James A. Bianco 2015-12-23