X0304 4 2011-12-31 0 0000891293 CELL THERAPEUTICS INC CTIC 0001198559 GREGORIAN VARTAN 501 ELLIOTT AVE W, SUITE 400 SEATTLE WA 98119 1 0 0 0 Common Stock 2011-12-31 4 D 0 166109 0 D 357004 D Common Stock 2012-01-03 4 A 0 516360 0 A 873364 D Represents the forfeiture back to CTIC of shares of restricted stock. The restricted shares were originally awarded on July 12, 2010 and were subject to performance-based vesting conditions that were not satisfied. As disclosed by CTIC in Form 8-K filed 12/1/11, CTIC granted a bonus opportunity, effective 1/3/12, to the reporting person that is payable in shares of CTIC stock upon the achievement of certain performance goals. These goals include market capitalization and other goals, with the number of shares payable based on the number of shares of CTIC common stock outstanding at the time the particular goal is achieved. A portion of this bonus opportunity was granted in the form of an award of performance-based restricted stock. The shares reported above on this Form 4 reflect the grant of this restricted stock award that is subject to the same performance-based vesting requirements as described in the Form 8-K for the bonus opportunity generally. The number of shares that would otherwise be paid on achievement of a particular performance goal will be reduced by the number of any related restricted shares that vest in connection with the attainment of that goal. Louis A. Bianco, Attorney-in-fact for Vartan Gregorian 2012-01-04