Exhibit 32.2

Section 1350 Certification of the Chief Financial Officer

In connection with this Quarterly Report of Sterling Bancshares, Inc. (the “Company”) on Form 10-Q for the period ending March 31, 2008 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Zach L. Wasson, Executive Vice President and Chief Financial Officer of the Company, certify, pursuant to 18 U.S.C. Section 1350 that:

1. The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

2. The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Dated: May 9, 2008	By:	/s/ Zach L. Wasson
		Zach L. Wasson
		Executive Vice President
		and Chief Financial Officer