X0202 4 2007-05-23 1 0000890465 NPS PHARMACEUTICALS INC NPSP 0001206369 KLEIN JOSEPH III 383 COLOROW DRIVE SALT LAKE CITY UT 84108 0 0 0 1 as of May 22, 2007 Common Stock 2007-05-23 4 S 0 3100 4.10 D 35000 D Common Stock 2007-05-23 4 S 0 10000 4.0525 D 25000 D Common Stock 2007-05-23 4 S 0 10000 4.0521 D 15000 D Common Stock 2007-05-23 4 S 0 15000 4.0609 D 0 D Deferred Stock Units 0 Common Stock 49293 49293 D Mr. Klein ceased to be a Director on May 22, 2007 with the reduction in size of the Board of Directors and Mr. Klein not standing for re-election at the Annual Meeting of Stockholders. Mr. Klein has had no transactions in NPS stock within the previous six months or within the six months prior to cessation of director status. This transaction was not arranged prior to cessation of director status. Deferred Stock Units awarded under the Company's Nonemployee Director Compensation Program will be released six months after the date of separation from service as a director. Joseph Klein, III 2007-05-25